Association of Adiponectin Receptor (Adipo-R1/-R2) Expression and Colorectal Cancer

Obesity and Asthma: Adiponectin Receptor 1 (Adipo R1) and Adiponectin Receptor 2 (Adipo R2) are expressed by normal human bronchial epithelial (NHBE) cells at air-liquid interface (ALI) and expression changes with IL-13 stimulation

OBESITY AND ASTHMA: ADIPONECTIN RECEPTOR 1 (ADIPO R1) AND ADIPONECTIN RECEPTOR 2 (ADIPO R2) ARE EXPRESSED BY NORMAL HUMAN BRONCHIAL EPITHELIAL (NHBE) CELLS AT AIR-LIQUID INTERFACE (ALI) AND EXPRESSION CHANGES WITH IL-13 STIMULATION By Jennifer Bradley, M.S. A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science, at Virginia Commonwealth University. Vir...

Association of CD166 expression with clinicopathologic characteristics of colorectal cancer

Adiponectin Effect on The Viability of Human Endometrial Stromal Cells and mRNA Expression of Adiponectin Receptors

BACKGROUND Adiponectin is one of the most important adipokines secreted from fatty tissue that has a direct inhibitory effect on the development of cancer cells. Adiponectin plays an important role in human reproduction system and fertility of women. Adiponectin concentration decreases in women with endometriosis and endometrial cancer. The aim of the present study was to investigate the effect...

Evaluating the expression and prognostic value of TRAIL-R1 and TRAIL-R2 in breast cancer.

PURPOSE The cell surface receptors tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and TRAIL-R2 transmit apoptotic signals, and agents that activate these receptors are in clinical development. We sought to determine the expression and prognostic value of TRAIL-R1 and TRAIL-R2 in early-stage breast cancer. EXPERIMENTAL DESIGN Tissue microarrays containing specime...

TRAIL-induced apoptosis and expression of death receptor TRAIL-R1 and TRAIL-R2 in bladder cancer cells.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) is a member of TNF superfamily able to induce programmed death in cancer cells with no toxicity against normal tissues. TRAIL mediate apoptosis follows binding to the two death receptors, TRAIL-R1 (DR4) and/or TRAIL-R2 (DR5). In this study we investigated the cytotoxic and apoptotic effect of TRAIL on bladder cancer cells and...